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Exhibit 4.1 TENTH SUPPLEMENTAL INDENTURE

Addendum or Modifications

Exhibit 4.1 TENTH SUPPLEMENTAL INDENTURE | Document Parties: ALERE INC. | ALERE GENETICS, INC | ALERE HEALTH IMPROVEMENT COMPANY | ALERE HEALTH SYSTEMS, INC | ALERE HEALTH, LLC | ALERE HOME MONITORING, INC | ALERE INC | ALERE INTERNATIONAL HOLDING CORP | ALERE MEDICAL, INC | ALERE NEWCO II, INC | ALERE NEWCO, INC | ALERE NORTH AMERICA, INC | ALERE SAN DIEGO, INC | ALERE SCARBOROUGH, INC | ALERE TOXICOLOGY SERVICES, INC | ALERE US HOLDINGS, LLC | ALERE WELLBEING, INC | ALERE WELLOLOGY INC | ALERE WOMEN'S AND CHILDREN'S HEALTH, LLC | AMEDITECH INC | BINAX, INC | BIOSITE INCORPORATED | CHOLESTECH CORPORATION | FIRST CHECK DIAGNOSTICS CORP | FIRST CHECK ECOM, INC | HEMOSENSE, INC | ILLINOIS, INC | INNOVACON, INC | INSTANT TECHNOLOGIES, INC | INVERNESS MEDICAL, LLC | IVC INDUSTRIES, INC | NEW YORK, INC | QUALITY ASSURED SERVICES, INC | RMD NETWORKS, INC | RTL HOLDINGS, INC | SCIENTIFIC TESTING LABORATORIES, INC | SELFCARE TECHNOLOGY, INC | US BANK NATIONAL ASSOCIATION | WAMPOLE LABORATORIES, LLC | ZYCARE, INC You are currently viewing:
This Addendum or Modifications involves

ALERE INC. | ALERE GENETICS, INC | ALERE HEALTH IMPROVEMENT COMPANY | ALERE HEALTH SYSTEMS, INC | ALERE HEALTH, LLC | ALERE HOME MONITORING, INC | ALERE INC | ALERE INTERNATIONAL HOLDING CORP | ALERE MEDICAL, INC | ALERE NEWCO II, INC | ALERE NEWCO, INC | ALERE NORTH AMERICA, INC | ALERE SAN DIEGO, INC | ALERE SCARBOROUGH, INC | ALERE TOXICOLOGY SERVICES, INC | ALERE US HOLDINGS, LLC | ALERE WELLBEING, INC | ALERE WELLOLOGY INC | ALERE WOMEN'S AND CHILDREN'S HEALTH, LLC | AMEDITECH INC | BINAX, INC | BIOSITE INCORPORATED | CHOLESTECH CORPORATION | FIRST CHECK DIAGNOSTICS CORP | FIRST CHECK ECOM, INC | HEMOSENSE, INC | ILLINOIS, INC | INNOVACON, INC | INSTANT TECHNOLOGIES, INC | INVERNESS MEDICAL, LLC | IVC INDUSTRIES, INC | NEW YORK, INC | QUALITY ASSURED SERVICES, INC | RMD NETWORKS, INC | RTL HOLDINGS, INC | SCIENTIFIC TESTING LABORATORIES, INC | SELFCARE TECHNOLOGY, INC | US BANK NATIONAL ASSOCIATION | WAMPOLE LABORATORIES, LLC | ZYCARE, INC

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Title: Exhibit 4.1 TENTH SUPPLEMENTAL INDENTURE
Governing Law: New York     Date: 6/22/2011
Industry: Scientific and Technical Instr.     Sector: Technology

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Exhibit 4.1

          TENTH SUPPLEMENTAL INDENTURE (this “ Supplemental Indenture ”), dated as of June 16, 2011, among ALERE INC., a Delaware corporation (the “ Issuer ”), each of the Guarantors under the Indenture referred to below (the “ Guarantors ”), and U.S. BANK NATIONAL ASSOCIATION, as Trustee under the Indenture referred to below (the “ Trustee ”).

WITNESSETH:

          WHEREAS the Issuer has heretofore executed and delivered to the Trustee an Indenture dated as of May 12, 2009, as amended, supplemented and modified by a First Supplemental Indenture dated as of May 12, 2009, a Second Supplemental Indenture dated as of June 9, 2009, a Third Supplemental Indenture dated as of August 4, 2009, a Fourth Supplemental Indenture dated as of September 22, 2009, a Fifth Supplemental Indenture dated as of November 25, 2009, a Sixth Supplemental Indenture dated as of February 1, 2010, a Seventh Supplemental Indenture dated as of March 1, 2010 and an Eighth Supplemental Indenture dated as of March 19, 2010 (as so amended, supplemented and modified, and as further amended, supplemented or modified to date, the “ Indenture ”), by and among the Issuer, the Guarantors and the Trustee, providing for the issuance of 9.00% Senior Subordinated Notes due 2016 (the “ Notes ”);

          WHEREAS, pursuant to that certain Consent Solicitation Statement dated May 31, 2011, as amended and supplemented to date (the “ Consent Solicitation Statement ”), the Issuer solicited the consents of the holders of the Notes to the Record Date Amendments and Waivers (as defined in the Consent Solicitation Statement) with respect to the Indenture;

          WHEREAS, the approval by written consent of the holders of at least a majority of the aggregate principal amount of the Notes outstanding as of April 29, 2011 (the “ Record Date ”), which is the record date fixed by the Issuer in accordance with Section 9.05 of the Indenture, of which record date the Trustee has been duly notified in writing by the Issuer in accordance with Section 9.05, is sufficient to approve the aforesaid Record Date Amendments and Waivers in accordance with the Indenture;

          WHEREAS, having received the approval of the holders of at least a majority of the aggregate principal amount of the Notes outstanding as of the Record Date (the “ Requisite Consent ”) pursuant to Section 9.02(a) of the Indenture with respect to the Record Date Amendments and Waivers, the Issuer, the Guarantors and the Trustee desire to effect the Record Date Amendments and Waivers as provided hereinafter;

          WHEREAS, all conditions precedent set forth in the Consent Solicitation Statement and the Indenture to the execution and delivery of this of this Supplemental Indenture by the Issuer, the Guarantors and the Trustee have been satisfied, and all things necessary have been done to make this Tenth Supplemental Indenture, when executed and delivered by the Issuers and the Guarantors, the legal, valid and binding agreement of the Issuers and the Guarantors, in accordance with its terms; and

          WHEREAS, the Issuer and the Guarantors have requested that the Trustee execute and deliver this Tenth Supplemental Indenture;

 


 

          NOW, THEREFORE in consideration of the foregoing and for other good and valuable consideration, the receipt of which is hereby acknowledged, the parties to this Tenth Supplemental Indenture hereby agree as follows:

          SECTION 1. Definitions . For all purposes of this Supplemental Indenture, except as otherwise herein expressly provided or unless the context otherwise requires: (i) the terms and expressions used herein shall have the same meanings as corresponding terms and expressions used in the Indenture; and (ii) the words “herein,” “hereof” and “hereby” and other words of similar import used in this Supplemental Indenture refer to this Supplemental Indenture as a whole and not to any particular section hereof.

          SECTION 2.


 
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