Amgen

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1) FOURTH AMENDMENT TO DEVELOPMENT AND LICENSE AGREEMENT

Parties: NPS PHARMACEUTICALS INC | Amgen Inc | Cinacalcet Royalty Sub LLC | NPS Pharmaceuticals, Inc
Document Date: 8/15/2011
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

2) Micromet Announces Solid Tumor BiTE Antibody Collaboration with Amgen - Collaboration on up to three targets and two programs - Upfront payment of ?10 million upon deal execution - Maximum deal value of ?695 million plus royalties and development cost reimbursement

Parties: MICROMET, INC. | Amgen Inc | Rockville, MD, July 11, 2011 -Micromet, Inc
Document Date: 7/15/2011
Industry: Biotechnology and Drugs
Sector: Healthcare

3) AMGEN INC. CHANGE OF CONTROL SEVERANCE PLAN

Parties: AMGEN INC
Document Date: 5/10/2011
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

4) FIRST AMENDMENT TO THE AGREEMENT AND PLAN OF MERGER

Parties: AMGEN INC | Andromeda Acquisition Corp | BioVex Group, Inc | BioVex Limited | Forbion 1 Management BV
Law Firm: Wilmer Cutler;Sullivan Cromwell
Document Date: 5/10/2011
Industry: Biotechnology and Drugs
Sector: Healthcare

5) AGREEMENT AND PLAN OF MERGER among

Parties: AMGEN INC | ANDROMEDA ACQUISITION CORP | BIOVEX GROUP, INC | BIOVEX LIMITED | Forbion 1 Management BV | Forbion Capital Partners
Law Firm: Goodwin Procter;Wilmer Cutler;Sullivan Cromwell
Document Date: 5/10/2011
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

6) SUPPLY, DEDICATED SUITE AND MANUFACTURING GUARANTEE AGREEMENT by and between Nektar Therapeutics and Amgen Inc. and Amgen Manufacturing, Limited dated October 29, 2010

Parties: NEKTAR THERAPEUTICS | Amgen Manufacturing, Limited | Nektar and Amgen Inc
Document Date: 3/1/2011
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

7) LICENSE AND ASSIGNMENT AGREEMENT

Parties: CELLDEX THERAPEUTICS, INC. | AMGEN INC | CELLDEX THERAPEUTICS, INC
Document Date: 12/23/2010
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

8) AMGEN INC. CHANGE OF CONTROL SEVERANCE PLAN

Parties: AMGEN INC
Document Date: 12/15/2010
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

9) AMENDMENT NO. 1 TO CREDIT AGREEMENT

Parties: AMGEN INC | Citicorp USA, Inc
Document Date: 8/10/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York

10) Second Restated Collaboration Agreement

Parties: Abgenix, Inc | Amgen Fremont Inc | CuraGen Corporation
Document Date: 8/5/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

11) AMENDMENT NO. 7 TO THE ENBREL SUPPLY AGREEMENT

Parties: AMGEN INC | IMMUNEX CORPORATION | Wyeth Pharmaceuticals
Document Date: 5/11/2009
Industry: Biotechnology and Drugs
Sector: Healthcare

12) AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM

Parties: AMGEN INC
Document Date: 5/8/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

13) AMGEN INC. 2009 DIRECTOR EQUITY INCENTIVE PROGRAM

Parties: AMGEN INC
Document Date: 5/8/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

14) RESTRICTED STOCK UNIT AGREEMENT

Parties: AMGEN INC
Document Date: 5/8/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

15) GRANT OF NON-QUALIFIED STOCK OPTION

Parties: AMGEN INC
Document Date: 5/8/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

16) MASTER SERVICES AGREEMENT

Parties: AMGEN INC | International Business Machines Corporation
Document Date: 2/27/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

17) GRANT OF NONQUALIFIED STOCK OPTION

Parties: AMGEN INC
Document Date: 2/27/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

18) AMENDMENT AND RESTATEMENT OF THE AMGEN CHANGE OF CONTROL SEVERANCE PLAN EFFECTIVE DECEMBER 9, 2008

Parties: AMGEN INC
Document Date: 2/27/2009
Industry: Biotechnology and Drugs
Sector: Healthcare

19) INTEGRATED FACILITIES MANAGEMENT SERVICES AGREEMENT

Parties: AMGEN INC | Jones Lang LaSalle Americas, Inc
Document Date: 2/27/2009
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

20) AMGEN INC. EXECUTIVE INCENTIVE PLAN

Parties: AMGEN INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

21) AMGEN INC. AMENDED AND RESTATED 1991 EQUITY INCENTIVE PLAN

Parties: AMGEN INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare

22) Amgen Nonqualified Deferred Compensation Plan As Amended and Restated Effective January 1, 2009

Parties: AMGEN INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

23) AMGEN INC. EXECUTIVE NONQUALIFIED RETIREMENT PLAN

Parties: AMGEN INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

24) AMGEN INC. AMENDED AND RESTATED 1999 INCENTIVE STOCK PLAN

Parties: AMGEN INC | Abgenix, Inc | Athletics Merger Sub, Inc
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare

25) AMGEN INC. AMENDED AND RESTATED 1999 EQUITY INCENTIVE PLAN

Parties: AMGEN INC | Immunex Corporation
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Washington

26) GRANT OF STOCK OPTION AGREEMENT

Parties: AMGEN INC
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

27) AMENDMENT NO. 2 TO AMENDMENT NO. 6 TO THE ENBREL�SUPPLY AGREEMENT

Parties: AMGEN INC | American Home Products Corporation | IMMUNEX CORPORATION | Wyeth Pharmaceuticals
Document Date: 11/7/2008
Industry: Biotechnology and Drugs
Sector: Healthcare

28) VARIABLE TERM ACCELERATED SHARE REPURCHASE TRANSACTION

Parties: AMGEN INC | Lehman Brothers Inc | Lehman Brothers OTC Derivatives Inc | Securities Investor Protection Corporation
Document Date: 8/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York

29) AMENDMENT NO. 1 TO AMENDMENT NO. 2 TO THE ENBREL� SUPPLY AGREEMENT

Parties: AMGEN INC | American Home Products Corporation | BOEHRINGER INGELHEIM PHARMA GMBH & CO | IMMUNEX CORPORATION | Wyeth Pharmaceuticals
Document Date: 8/8/2008
Industry: Biotechnology and Drugs
Sector: Healthcare

30) SALE AND PURCHASE AGREEMENT

Parties: AMGEN INC | Takeda Pharmaceutical Company Limited
Law Firm: Sullivan Cromwell
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York

31) License Agreement

Parties: AMGEN INC | Takeda Pharmaceutical Company Limited
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

32) Supply Agreement

Parties: AMGEN INC | Takeda Pharmaceutical Company Limited
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

33) License Agreement

Parties: AMGEN INC | Takeda Pharmaceutical Company Limited
Document Date: 5/12/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

34) AGREEMENT OF RESIGNATION, APPOINTMENT AND ACCEPTANCE

Parties: AMGEN INC | Bank of New York | CITIBANK, NA
Document Date: 2/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York

35) AMGEN INC. AMENDED AND RESTATED DIRECTOR EQUITY INCENTIVE PROGRAM

Parties: AMGEN INC
Document Date: 2/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

36) GRANT OF STOCK OPTION

Parties: AMGEN INC
Document Date: 2/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

37) SECOND AMENDMENT TO THE AMGEN INC. AMENDED AND RESTATED EMPLOYEE STOCK PURCHASE PLAN

Parties: AMGEN INC
Document Date: 2/28/2008
Industry: Biotechnology and Drugs
Sector: Healthcare

38) FIRST AMENDMENT TO THE AMGEN INC. EXECUTIVE NONQUALIFIED RETIREMENT PLAN

Parties: AMGEN INC
Document Date: 11/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

39) FOURTH AMENDMENT TO THE AMGEN INC. SUPPLEMENTAL RETIREMENT PLAN

Parties: AMGEN INC
Document Date: 11/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

40) FOURTH AMENDMENT TO THE AMGEN NONQUALIFIED DEFERRED COMPENSATION PLAN

Parties: AMGEN INC
Document Date: 11/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

41) Collaboration Agreement

Parties: AMGEN INC | Daiichi Sankyo Company, Limited
Document Date: 11/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:California

42) CREDIT AGREEMENT

Parties: AMGEN INC | Barclays Bank PLC | Citicorp USA, Inc | Citibank, N.A. | CUSA
Law Firm: Latham Watkins;Shearman Sterling
Document Date: 11/2/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:New York

43) PERFORMANCE UNIT AGREEMENT

Parties: Amgen Inc
Document Date: 8/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

44) AMGEN INC. DIRECTOR EQUITY INCENTIVE PROGRAM

Parties: AMGEN INC
Document Date: 8/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare
Governing Law:Delaware

45) AMENDMENT NO. 13 TO THE SHAREHOLDERS' AGREEMENT

Parties: Kirin Brewery Company, Limited | Kirin Holdings Company, Limited | Kirin Pharma Company, Limited | Kirin-Amgen, Inc
Document Date: 8/9/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

46) AMGEN INC. ASSUMED ILYPSA, INC. STOCK PLAN

Parties: AMGEN INC | ASSUMED ILYPSA, INC
Document Date: 7/18/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

47) REGISTRATION RIGHTS AGREEMENT

Parties: AMGEN INC | MERRILL LYNCH, PIERCE, FENNER & SMITH INCORPORATED | MORGAN STANLEY & CO INCORPORATED
Document Date: 5/30/2007
Governing Law:New York

48) AMGEN PRICES $4 BILLION OF SENIOR NOTES IN THREE SERIES; COMPANY TO PURCHASE APPROXIMATELY $3 BILLION IN COMMON STOCK

Parties: AMGEN INC
Document Date: 5/25/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

49) EX-10.52 FIRST AMENDMENT TO LICENSE AGREEMENT BETWEEN AMGEN INC. AND EPIX PHARMACEUTICALS, INC.

Parties: EPIX PHARMACEUTICALS, INC. | AMGEN INC.
Document Date: 4/10/2007
Industry: Biotechnology and Drugs
Sector: Healthcare

50) Collaboration and Option Agreement

Parties: Amgen Inc | Cytokinetics, Incorporated
Law Firm: Wilson Sonsini
Document Date: 3/12/2007
Governing Law:California

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